Drug Screening and Discovery using Zebrafish as an Animal Model

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Zebrafish
Time vs. Distance Moved

 

Epilepsy: Using stablished methods in 5 dpf larvae to identify efficient compounds to cure epilepsy.

Diabetes: Glucose measurement in 7 dpf larvae to identify the compounds which are efficient in lowering glucose level.

Brain Micro-bleeding (BMB)/Intracerebral Hemorrhage (ICH): Using stablished methods to identify efficient compounds to rescue the bleeding in 3 dpf larvae.

Parkinson/Alzheimer: Using MPP+ model to identify potential drugs in 5 dpf larvae

StressAssessment of locomotor activity and photomotor response in 5 dpf larvae by performing alternating light/dark locomotion assay using DanioVision Noldus tracking system to identify efficient compounds

Wound Healing: Tailfin transection in 4 dpf larvae and assaying its healing 4 and 6 days after wounding to identify efficient compounds

Anti-oxidation: In-vivo anti-oxidation assays in 3 dpf larvae to identify antioxidants for pharma and cosmetics

Melanin Quantification: Using stablished methods in 2 dpf larvae to identify whitening-agents for cosmetics

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