Wound healing is the process by which the body repairs damaged skin or tissue. It involves several stages: hemostasis, inflammation, proliferation, and remodeling. Delayed or impaired wound healing can lead to chronic conditions such as diabetic ulcers. Globally, around 1-2% of the population suffers from chronic wounds, with a large proportion in North America. The wound care market is valued at $20 billion globally. Current treatments include antibiotic creams, dressings, and growth factors. Companies have a significant opportunity to develop advanced wound healing therapies, as new drugs could offer better, faster healing, especially for chronic, non-healing wounds in diabetic patients and the aging population.
Zebrafish Model: Tailfin transection in 4 dpf larvae and assaying its healing 4 and 6 days after wounding to identify efficient compounds